I ran through this, and on reassembly the home button didn’t function properly. I found a link that said if you used alcohol to clean the edges in preparation for the new seal, that the alcohol will affect the home button. Drying it out gently with a light blast of compressed or warm air should resolve this. For me it didn’t. Next link I found warned that if the home button screw was too tight try backing it out and retightening it just to the point of resistance. Doing that restored the home button functionality.

One other tip: reinstall the haptic generator before installing the battery to ensure the correct battery placement.

Great instructions! Thanks iFixIt!